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The expression of BRCA1, P53, KAI1, and Nm23 in ovaries of BRCA1 mutation carriers after prophylactic adnexectomy

INTRODUCTION: High mortality rate, absence of reliable methods for early diagnosis and poor prognosis of advanced ovarian cancer prompted to investigate the role of prophylactic oophorectomy in BRCA1 mutation carriers as well as evaluate the expression of BRCA1, p53, Nm23, and KAI1 proteins in ovari...

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Autors principals: Markowska, J., Bar, J., Mądry, R., Słomska, I., Mardas, M., Grabowski, J. P.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778227/
https://ncbi.nlm.nih.gov/pubmed/23553196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00404-013-2825-9
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