Intranasal Delivery of Plasma and Platelet Growth Factors Using PRGF-Endoret System Enhances Neurogenesis in a Mouse Model of Alzheimer’s Disease

Neurodegeneration together with a reduction in neurogenesis are cardinal features of Alzheimer’s disease (AD) induced by a combination of toxic amyloid-β peptide (Aβ) and a loss of trophic factor support. Amelioration of these was assessed with diverse neurotrophins in experimental therapeutic appro...

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Detalhes bibliográficos
Main Authors: Anitua, Eduardo, Pascual, Consuelo, Pérez-Gonzalez, Rocio, Antequera, Desiree, Padilla, Sabino, Orive, Gorka, Carro, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777974/
https://ncbi.nlm.nih.gov/pubmed/24069173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073118
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