A TNF Variant that Associates with Susceptibility to Musculoskeletal Disease Modulates Thyroid Hormone Receptor Binding to Control Promoter Activation

Tumor necrosis factor (TNF) is a powerful pro-inflammatory cytokine and immuno-regulatory molecule, and modulates susceptibility to musculoskeletal diseases. Several meta-analyses and replicated association studies have implicated the minor ‘A’ variant within the TNF promoter single nucleotide polym...

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Библиографические подробности
Главные авторы: Kiss-Toth, Endre, Harlock, Edward, Lath, Darren, Quertermous, Thomas, Wilkinson, J. Mark
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777919/
https://ncbi.nlm.nih.gov/pubmed/24069456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076034
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