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Wiskott-Aldrich Syndrome protein regulates leukocyte-dependent breast cancer metastasis
A paracrine interaction between EGF-secreting tumor-associated macrophages (TAMs) and CSF-1-secreting breast carcinoma cells promotes invasion and metastasis. Here we show that mice deficient in the hematopoietic cell-specific Wiskott-Aldrich Syndrome protein (WASp), are unable to support TAM-depend...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3777703/ https://ncbi.nlm.nih.gov/pubmed/23911287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.07.007 |
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