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Amoeboid T lymphocytes Require the Septin Cytoskeleton for Cortical Integrity and Persistent Motility

The systems that refine actomyosin forces during motility remain poorly understood. Septins assemble on the T cell cortex and are enriched at the mid-zone in filaments. Septin knockdown causes membrane blebbing, excess leading edge protrusions, and lengthening of the trailingedge uropod. The associa...

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Autors principals: Tooley, Aaron J., Gilden, Julia, Jacobelli, Jordan, Beemiller, Peter, Trimble, William S., Kinoshita, Makoto, Krummel, Matthew F.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777658/
https://ncbi.nlm.nih.gov/pubmed/19043408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1808
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