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Retention of structure, antigenicity, and biological function of pneumococcal surface protein A (PspA) released from polyanhydride nanoparticles

Pneumococcal surface protein A (PspA) is a choline-binding protein which is a virulence factor found on the surface of all Streptococcus pneumoniae strains. Vaccination with PspA has been shown to be protective against a lethal challenge with S. pneumoniae, making it a promising immunogen for use in...

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Detalhes bibliográficos
Main Authors: Haughney, Shannon L., Petersen, Latrisha K., Schoofs, Amy D., Ramer-Tait, Amanda E., King, Janice, Briles, David, Wannemuehler, Michael J., Narasimhan, Balaji
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777629/
https://ncbi.nlm.nih.gov/pubmed/23774257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2013.06.006
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