The Satb1 protein directs hematopoietic stem cell differentiation toward lymphoid lineages

How hematopoietic stem cells (HSCs) produce particular lineages is insufficiently understood. We searched for key factors that direct HSC to lymphopoiesis. Comparing gene expression profiles for HSCs and early lymphoid progenitors revealed that Satb1, a global chromatin regulator, was markedly induc...

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Huvudupphovsmän: Satoh, Yusuke, Yokota, Takafumi, Sudo, Takao, Kondo, Motonari, Lai, Anne, Kincade, Paul W., Kouro, Taku, Iida, Ryuji, Kokame, Koichi, Miyata, Toshiyuki, Habuchi, Yoko, Matsui, Keiko, Tanaka, Hirokazu, Matsumura, Itaru, Oritani, Kenji, Kohwi-Shigematsu, Terumi, Kanakura, Yuzuru
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777575/
https://ncbi.nlm.nih.gov/pubmed/23791645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.05.014
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