The Satb1 protein directs hematopoietic stem cell differentiation toward lymphoid lineages

How hematopoietic stem cells (HSCs) produce particular lineages is insufficiently understood. We searched for key factors that direct HSC to lymphopoiesis. Comparing gene expression profiles for HSCs and early lymphoid progenitors revealed that Satb1, a global chromatin regulator, was markedly induc...

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Main Authors: Satoh, Yusuke, Yokota, Takafumi, Sudo, Takao, Kondo, Motonari, Lai, Anne, Kincade, Paul W., Kouro, Taku, Iida, Ryuji, Kokame, Koichi, Miyata, Toshiyuki, Habuchi, Yoko, Matsui, Keiko, Tanaka, Hirokazu, Matsumura, Itaru, Oritani, Kenji, Kohwi-Shigematsu, Terumi, Kanakura, Yuzuru
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777575/
https://ncbi.nlm.nih.gov/pubmed/23791645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.05.014
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