The Satb1 protein directs hematopoietic stem cell differentiation toward lymphoid lineages

How hematopoietic stem cells (HSCs) produce particular lineages is insufficiently understood. We searched for key factors that direct HSC to lymphopoiesis. Comparing gene expression profiles for HSCs and early lymphoid progenitors revealed that Satb1, a global chromatin regulator, was markedly induc...

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Main Authors: Satoh, Yusuke, Yokota, Takafumi, Sudo, Takao, Kondo, Motonari, Lai, Anne, Kincade, Paul W., Kouro, Taku, Iida, Ryuji, Kokame, Koichi, Miyata, Toshiyuki, Habuchi, Yoko, Matsui, Keiko, Tanaka, Hirokazu, Matsumura, Itaru, Oritani, Kenji, Kohwi-Shigematsu, Terumi, Kanakura, Yuzuru
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777575/
https://ncbi.nlm.nih.gov/pubmed/23791645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.05.014
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