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Role of ABC transporters in cancer chemotherapy

Multidrug resistance (MDR) in cancer cells can significantly attenuate the response to chemotherapy and increase the likelihood of mortality. The major mechanism involved in conferring MDR is the overexpression of ATP-binding cassette (ABC) transporters, which can increase efflux of drugs from cance...

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Detalhes bibliográficos
Main Authors: Sun, Yue-Li, Patel, Atish, Kumar, Priyank, Chen, Zhe-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Sun Yat-sen University Cancer Center 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777472/
https://ncbi.nlm.nih.gov/pubmed/22257384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.011.10466
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