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Depression: A repair response to stress-induced neuronal microdamage that can grade into a chronic neuroinflammatory condition?

Depression is a major contributor to the global burden of disease and disability, yet it is poorly understood. Here we review data supporting a novel theoretical model for the biology of depression. In this model, a stressful life event leads to microdamage in the brain. This damage triggers an inju...

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Detalhes bibliográficos
Main Authors: Wager-Smith, Karen, Markou, Athina
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777427/
https://ncbi.nlm.nih.gov/pubmed/20883718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neubiorev.2010.09.010
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