Impact of body mass index on estradiol depletion by aromatase inhibitors in postmenopausal women with early breast cancer

BACKGROUND: Body mass index (BMI) has an impact on survival outcome in patients treated with aromatase inhibitors (AIs). Obesity is associated with an increased body aromatisation and may be a cause of insufficient estradiol depletion. METHODS: Sixty-eight postmenopausal oestrogen receptor-positive...

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Главные авторы: Pfeiler, G, Königsberg, R, Hadji, P, Fitzal, F, Maroske, M, Dressel-Ban, G, Zellinger, J, Exner, R, Seifert, M, Singer, C, Gnant, M, Dubsky, P
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2013
Предметы:
Clinical Study
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3777005/
https://ncbi.nlm.nih.gov/pubmed/24002592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.499
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