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Hepatitis C Virus Replication and Golgi Function in Brefeldin A-Resistant Hepatoma-Derived Cells

Recent reports indicate that the replication of hepatitis C virus (HCV) depends on the GBF1-Arf1-COP-I pathway. We generated Huh-7-derived cell lines resistant to brefeldin A (BFA), which is an inhibitor of this pathway. The resistant cell lines could be sorted into two phenotypes regarding BFA-indu...

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Detalhes bibliográficos
Main Authors: Farhat, Rayan, Goueslain, Lucie, Wychowski, Czeslaw, Belouzard, Sandrine, Fénéant, Lucie, Jackson, Catherine L., Dubuisson, Jean, Rouillé, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776844/
https://ncbi.nlm.nih.gov/pubmed/24058576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074491
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