Detection of Phospho-Sites Generated by Protein Kinase CK2 in CFTR: Mechanistic Aspects of Thr1471 Phosphorylation

By mass spectrometry analysis of mouse Cystic Fibrosis Transmembrane-conductance Regulator (mCFTR) expressed in yeast we have detected 21 phosphopeptides accounting for 22 potential phospho-residues, 12 of which could be unambiguously assigned. Most are conserved in human CFTR (hCFTR) and the majori...

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Main Authors: Venerando, Andrea, Franchin, Cinzia, Cant, Natasha, Cozza, Giorgio, Pagano, Mario A., Tosoni, Kendra, Al-Zahrani, Ateeq, Arrigoni, Giorgio, Ford, Robert C., Mehta, Anil, Pinna, Lorenzo A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776838/
https://ncbi.nlm.nih.gov/pubmed/24058532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074232
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