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Efficient TALEN Construction for Bombyx mori Gene Targeting
Engineered nucleases are artificial enzymes able to introduce double stranded breaks at desired genomic locations. The double stranded breaks start the error-prone repair process of non-homologous end-joining (NHEJ), which eventually leads to the induction of mutations at target sites. We showed ear...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3776831/ https://ncbi.nlm.nih.gov/pubmed/24058473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073458 |
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