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Efficient TALEN Construction for Bombyx mori Gene Targeting

Engineered nucleases are artificial enzymes able to introduce double stranded breaks at desired genomic locations. The double stranded breaks start the error-prone repair process of non-homologous end-joining (NHEJ), which eventually leads to the induction of mutations at target sites. We showed ear...

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Detalhes bibliográficos
Main Authors: Takasu, Yoko, Sajwan, Suresh, Daimon, Takaaki, Osanai-Futahashi, Mizuko, Uchino, Keiro, Sezutsu, Hideki, Tamura, Toshiki, Zurovec, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776831/
https://ncbi.nlm.nih.gov/pubmed/24058473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073458
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