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The Hierarchical Process of Differentiation of Long-Lived Antibody-Secreting Cells Is Dependent on Integrated Signals Derived from Antigen and IL-17A

Switched CD19-positive memory B cells purified from mice with chronic immune response against Thalassophryne nattereri venom proteins were cultured with venom or cytokines. Our results confirm the existence of a hierarchic process of differentiation: activated memory B cells progressively acquire in...

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Détails bibliographiques
Auteurs principaux: Grund, Lidiane Zito, Lopes-Ferreira, Monica, Lima, Carla
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776816/
https://ncbi.nlm.nih.gov/pubmed/24058589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074566
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