A Fully Human Inhibitory Monoclonal Antibody to the Wnt Receptor RYK

RYK is an unusual member of the receptor tyrosine kinase (RTK) family that is classified as a putative pseudokinase. RYK regulates fundamental biological processes including cell differentiation, migration and target selection, axon outgrowth and pathfinding by transducing signals across the plasma...

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Bibliografiske detaljer
Main Authors: Halford, Michael M., Macheda, Maria L., Parish, Clare L., Takano, Elena A., Fox, Stephen, Layton, Daniel, Nice, Edouard, Stacker, Steven A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776778/
https://ncbi.nlm.nih.gov/pubmed/24058687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075447
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