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Genome-wide analysis of murine bone marrow-derived very small embryonic-like stem cells reveals that mitogenic growth factor signaling pathways play a crucial role in the quiescence and ageing of these cells
It has been postulated that the most primitive population of stem cells, Oct4(+)Sca-1(+)Lin(−)CD45(−) very small embryonic-like stem cells (VSELs), differentiate into tissue-committed stem cells in adult mice. However, Oct4(+) VSELs remain quiescent in adult tissues and do not form teratomas. In thi...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
D.A. Spandidos
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3776718/ https://ncbi.nlm.nih.gov/pubmed/23708325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2013.1389 |
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