Oxaliplatin induces different cellular and molecular chemoresistance patterns in colorectal cancer cell lines of identical origins

BACKGROUND: Cancer cells frequently adopt cellular and molecular alterations and acquire resistance to cytostatic drugs. Chemotherapy with oxaliplatin is among the leading treatments for colorectal cancer with a response rate of 50%, inducing intrastrand cross-links on the DNA. Despite of this drug’...

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Main Authors: Virag, Piroska, Fischer-Fodor, Eva, Perde-Schrepler, Maria, Brie, Ioana, Tatomir, Corina, Balacescu, Loredana, Berindan-Neagoe, Ioana, Victor, Bogdan, Balacescu, Ovidiu
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776436/
https://ncbi.nlm.nih.gov/pubmed/23865481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-480
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