A novel B cell population revealed by a CD38/CD24 gating strategy: CD38(−)CD24(−) B cells in centenarian offspring and elderly people

The B cell arm of adaptive immunity undergoes significant modifications with age. Elderly people are characterized by impaired B cell responses reflected in a reduced ability to effectively respond against viruses and bacteria. Alterations of immunity with advancing age (immunosenescence) have been...

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Main Authors: Buffa, Silvio, Pellicanò, Mariavaleria, Bulati, Matteo, Martorana, Adriana, Goldeck, David, Caruso, Calogero, Pawelec, Graham, Colonna-Romano, Giuseppina
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776115/
https://ncbi.nlm.nih.gov/pubmed/23129025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9488-5
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