Selective Matrix (Hyaluronan) Interaction with CD44 and RhoGTPase Signaling Promotes Keratinocyte Functions and Overcomes Age-related Epidermal Dysfunction

BACKGROUND: Mouse epidermal chronologic aging is closely associated with aberrant matrix (hyaluronan, HA) -size distribution/production and impaired keratinocyte proliferation/differentiation, leading to a marked thinning of the epidermis with functional consequence that causes a slower recovery of...

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Autores principales: Bourguignon, Lilly Y.W., Wong, Gabriel, Xia, Weiliang, Man, Mao-Qiang, Holleran, Walter M., Elias, Peter M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775883/
https://ncbi.nlm.nih.gov/pubmed/23790635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdermsci.2013.05.003
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