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RNA-based fluorescent biosensors for live cell imaging of second messengers cyclic di-GMP and cyclic AMP-GMP

Cyclic di-nucleotides are an important class of signaling molecules that regulate a wide variety of pathogenic responses in bacteria, but tools for monitoring their regulation in vivo are lacking. We have designed fluorescent RNA-based biosensors for cyclic di-GMP and cyclic AMP-GMP by fusing the Sp...

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Autors principals: Kellenberger, Colleen A., Wilson, Stephen C., Sales-Lee, Jade, Hammond, Ming C.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775879/
https://ncbi.nlm.nih.gov/pubmed/23488798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311960g
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