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Influence of Secondary Structure on In-Source Decay of Protein in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

The susceptibility of the N–C(α) bond of the peptide backbone to specific cleavage by in-source decay (ISD) in matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) was studied from the standpoint of the secondary structure of three proteins. A naphthalene derivative, 5-amino-1-na...

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Detalles Bibliográficos
Main Authors: Takayama, Mitsuo, Osaka, Issey, Sakakura, Motoshi
Formato: Artigo
Idioma:Inglês
Publicado: The Mass Spectrometry Society of Japan 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775823/
https://ncbi.nlm.nih.gov/pubmed/24349902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5702/massspectrometry.A0001
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