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Association between DNA Methyltransferases 3B Gene Polymorphisms and the Susceptibility to Acute Myeloid Leukemia in Chinese Han Population

DNMT3B plays a crucial role in the generation of aberrant methylation during carcinogenesis. Polymorphisms in the DNMT3B gene may influence the DNA methylation enzymatic activity of DNMT3B, thereby modulating the susceptibility to AML. Thus, we investigated the association between SNPs in the DNMT3B...

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Main Authors: Zheng, Qin, Zeng, Ting-ting, Chen, Jiao, Liu, Hua, Zhang, He, Su, Jun
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775800/
https://ncbi.nlm.nih.gov/pubmed/24069326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074626
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