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Association between DNA Methyltransferases 3B Gene Polymorphisms and the Susceptibility to Acute Myeloid Leukemia in Chinese Han Population

DNMT3B plays a crucial role in the generation of aberrant methylation during carcinogenesis. Polymorphisms in the DNMT3B gene may influence the DNA methylation enzymatic activity of DNMT3B, thereby modulating the susceptibility to AML. Thus, we investigated the association between SNPs in the DNMT3B...

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Bibliografiske detaljer
Main Authors: Zheng, Qin, Zeng, Ting-ting, Chen, Jiao, Liu, Hua, Zhang, He, Su, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775800/
https://ncbi.nlm.nih.gov/pubmed/24069326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074626
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