Age-dependent changes in 8-oxoguanine-DNA-glycosylase activity is modulated by adaptive responses to physical exercise in human skeletal muscle

8-Oxo-7,8 dihydroguanine (8-oxoG) accumulates in the genome over time and is believed to contribute to the development of aging characteristics of skeletal muscle and various aging-related diseases. Here, we show a significantly increased level of intrahelical 8-oxoG and 8-oxoguanine DNA glycosylase...

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Detalhes bibliográficos
Main Authors: Radak, Zsolt, Bori, Zoltan, Koltai, Erika, Fatouros, Ioannis G., Jamurtas, Athanasios Z., Douroudos, Ioannis I., Terzis, Gerasimos, Nikolaidis, Michalis G., Chatzinikolaou, Athanasios, Sovatzidis, Apostolos, Kumagai, Shuzo, Naito, Hisahi, Boldogh, Istvan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775599/
https://ncbi.nlm.nih.gov/pubmed/21569841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.04.018
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