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Radiation-induced upregulation of telomerase activity escapes PI3-kinase inhibition in two malignant glioma cell lines
Tumor relapse after radiotherapy is a great concern in the treatment of high-grade gliomas. Inhibition of the PI3-kinase/AKT pathway is known to radiosensitize cancer cells and to delay their DNA repair after irradiation. In this study, we show that the radiosensitization of CB193 and T98G, two high...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
D.A. Spandidos
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3775596/ https://ncbi.nlm.nih.gov/pubmed/23727752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2013.1970 |
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