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Mapping Protein-Specific Micro-Environments in Live Cells by Fluorescence Lifetime Imaging of a Hybrid Genetic-Chemical Molecular Rotor Tag
The micro-viscosity and molecular crowding experienced by specific proteins can regulate dynamics and function within live cells. Taking advantage of the emerging TMP-tag technology, we present the design, synthesis and application of a hybrid genetic-chemical molecular rotor probe whose fluorescenc...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3775488/ https://ncbi.nlm.nih.gov/pubmed/22825488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc33133k |
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