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Effects of apoE Deficiency and Occlusal Disharmony on Amyloid-Beta Production and Spatial Memory in Rats

Amyloid-β (Aβ) plays a causative role in Alzheimer’s disease. Apolipoprotein E (apoE) is involved in Aβ accumulation, whereas occlusal disharmony increases Aβ production in the rat hippocampus. The purpose of the present study was to investigate the effects of apoE deficiency and occlusal disharmony...

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Bibliographic Details
Main Authors: Ekuni, Daisuke, Endo, Yasumasa, Tomofuji, Takaaki, Azuma, Tetsuji, Irie, Koichiro, Kasuyama, Kenta, Morita, Manabu
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774813/
https://ncbi.nlm.nih.gov/pubmed/24066161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074966
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