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Controlling Seizure-Like Events by Perturbing Ion Concentration Dynamics with Periodic Stimulation

We investigate the effects of adding periodic stimulation to a generic, conductance-based neuron model that includes ion concentration dynamics of sodium and potassium. Under conditions of high extracellular potassium, the model exhibits repeating, spontaneous, seizure-like bursting events associate...

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Bibliografiske detaljer
Main Authors: Owen, Jeremy A., Barreto, Ernest, Cressman, John R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774776/
https://ncbi.nlm.nih.gov/pubmed/24066075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073820
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