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Unique Anti-Glioblastoma Activities of Hypericin Are at the Crossroad of Biochemical and Epigenetic Events and Culminate in Tumor Cell Differentiation

Failure of conventional therapies to alleviate glioblastoma (GBM) fosters search for novel therapeutic strategies. These include epigenetic modulators as histone deacetylase inhibitors (HDACi), which relax abnormally compact tumor cell chromatin organization, enabling cells to overcome blockage in d...

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Bibliografske podrobnosti
Main Authors: Dror, Naama, Mandel, Mathilda, Lavie, Gad
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774735/
https://ncbi.nlm.nih.gov/pubmed/24066060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073625
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