Antigen presenting cells expressing Fas ligand down-modulate chronic inflammatory disease in Fas ligand–deficient mice

We assessed the effect of modified antigen presenting cells (APCs) expressing high levels of Fas ligand (APC-FasL) on post-viral chronic inflammatory disease. FasL-deficient B6-gld/gld mice infected with murine cytomegalovirus (MCMV) cleared the virus from their lungs, kidneys, and livers within 2 w...

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Main Authors: Zhang, Huang-Ge, Fleck, Martin, Kern, Earl R., Liu, Di, Wang, Yongming, Hsu, Hui-Chen, Yang, Pingar, Wang, Zheng, Curiel, David T., Zhou, Tong, Mountz, John D.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC377462/
https://ncbi.nlm.nih.gov/pubmed/10727450
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