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Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension

Reduced production of nitric oxide (NO) in the cirrhotic liver results from a defect in hepatic endothelial cell nitric oxide synthase (ecNOS) and appears to contribute to the high intrahepatic resistance and portal hypertension typical of cirrhosis. Therefore, we postulated that targeting a heterol...

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Hlavní autoři: Yu, Qing, Shao, Rong, Qian, Hu Sheng, George, Samuel E., Rockey, Don C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC377460/
https://ncbi.nlm.nih.gov/pubmed/10727442
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