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Acquisition of RGC phenotype in human Müller glia with stem cell characteristics is accompanied by upregulation of functional nicotinic acetylcholine receptors

PURPOSE: Human Müller glia with stem cell characteristics (hMGSCs) can be induced to express genes and proteins of retinal ganglion cells (RGCs) upon in vitro inhibition of Notch-1 activity. However, it is not known whether expression of these markers is accompanied by acquisition of RGC function. T...

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Detalhes bibliográficos
Main Authors: Becker, Silke, Singhal, Shweta, Jones, Megan F., Eastlake, Karen, Cottrill, Phillippa B., Jayaram, Hari, Limb, G. Astrid
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774575/
https://ncbi.nlm.nih.gov/pubmed/24049438
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