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Acquisition of RGC phenotype in human Müller glia with stem cell characteristics is accompanied by upregulation of functional nicotinic acetylcholine receptors

PURPOSE: Human Müller glia with stem cell characteristics (hMGSCs) can be induced to express genes and proteins of retinal ganglion cells (RGCs) upon in vitro inhibition of Notch-1 activity. However, it is not known whether expression of these markers is accompanied by acquisition of RGC function. T...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Becker, Silke, Singhal, Shweta, Jones, Megan F., Eastlake, Karen, Cottrill, Phillippa B., Jayaram, Hari, Limb, G. Astrid
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Molecular Vision 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774575/
https://ncbi.nlm.nih.gov/pubmed/24049438
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