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Leukocyte-derived extracellular superoxide dismutase does not contribute to airspace EC-SOD after interstitial pulmonary injury

The antioxidant enzyme extracellular superoxide dismutase (EC-SOD) is abundant in the lung and is known to limit inflammation and fibrosis following numerous pulmonary insults. Previous studies have reported a loss of full-length EC-SOD from the pulmonary parenchyma with accumulation of proteolyzed...

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Bibliographic Details
Main Authors: Manni, Michelle L., Epperly, Michael W., Han, Wei, Blackwell, Timothy S., Duncan, Steven R., Piganelli, Jon D., Oury, Tim D.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774542/
https://ncbi.nlm.nih.gov/pubmed/22003088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00360.2010
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