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Inter-ethnic differences in lymphocyte sensitivity to glucocorticoids reflect variation in transcriptional response
Glucocorticoids (GCs) are steroid hormones widely used as pharmaceutical interventions, which act mainly by regulating gene expression levels. A large fraction of patients (~30%), especially those of African descent, show a weak response to treatment. To interrogate the contribution of variable tran...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774530/ https://ncbi.nlm.nih.gov/pubmed/22158329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2011.55 |
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