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Syntaxin 1A is expressed in airway epithelial cells, where it modulates CFTR Cl(–) currents

The CFTR Cl(–) channel controls salt and water transport across epithelial tissues. Previously, we showed that CFTR-mediated Cl(–) currents in the Xenopus oocyte expression system are inhibited by syntaxin 1A, a component of the membrane trafficking machinery. This negative modulation of CFTR functi...

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Autors principals: Naren, Anjaparavanda P., Di, Anke, Cormet-Boyaka, Estelle, Boyaka, Prosper N., McGhee, Jerry R., Zhou, Weihong, Akagawa, Kimio, Fujiwara, Tomonori, Thome, Ulrich, Engelhardt, John F., Nelson, Deborah J., Kirk, Kevin L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC377449/
https://ncbi.nlm.nih.gov/pubmed/10675364
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