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Interaction of Aryl Hydrocarbon Receptor-interacting Protein-like 1 with the Farnesyl Moiety

Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) is a photoreceptor specific chaperone of the visual effector enzyme phosphodiesterase-6 (PDE6). AIPL1 has been shown to bind the farnesylated PDE6A subunit. Mutations in AIPL1 are thought to destabilize PDE6 and thereby cause Leber congeni...

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Détails bibliographiques
Auteurs principaux: Majumder, Anurima, Gopalakrishna, Kota N., Cheguru, Pallavi, Gakhar, Lokesh, Artemyev, Nikolai O.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774400/
https://ncbi.nlm.nih.gov/pubmed/23737531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.476242
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