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Breaking the Carboxyl Rule: LYSINE 96 FACILITATES REPROTONATION OF THE SCHIFF BASE IN THE PHOTOCYCLE OF A RETINAL PROTEIN FROM EXIGUOBACTERIUM SIBIRICUM

A lysine instead of the usual carboxyl group is in place of the internal proton donor to the retinal Schiff base in the light-driven proton pump of Exiguobacterium sibiricum (ESR). The involvement of this lysine in proton transfer is indicated by the finding that its substitution with alanine or oth...

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Autores principales: Balashov, Sergei P., Petrovskaya, Lada E., Imasheva, Eleonora S., Lukashev, Evgeniy P., Dioumaev, Andrei K., Wang, Jennifer M., Sychev, Sergey V., Dolgikh, Dmitriy A., Rubin, Andrei B., Kirpichnikov, Mikhail P., Lanyi, Janos K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774394/
https://ncbi.nlm.nih.gov/pubmed/23696649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.465138
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