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On the Occurrence of Hypomyelination in a Transgenic Mouse Model: A Consequence of the Myelin Basic Protein Promoter?

Central nervous system hypomyelination is a feature common to a number of transgenic (Tg) mouse lines that express a variety of unrelated exogenous (i.e. non-CNS) transgenes. In this report we document hypomyelination structurally by immunocytochemistry and functionally in the Tg line MBP-JE, which...

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Detalhes bibliográficos
Main Authors: Gaupp, Stefanie, Arezzo, Joseph, Dutta, Dipankar J., John, Gareth R., Raine, Cedric S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774272/
https://ncbi.nlm.nih.gov/pubmed/22082665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31823b188b
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