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Titin-based stiffening of muscle fibers in Ehlers-Danlos Syndrome
Objective: tenascin-X (TNX) is an extracellular matrix glycoprotein whose absence leads to Ehlers-Danlos Syndrome (EDS). TNX-deficient EDS patients present with joint hypermobility and muscle weakness attributable to increased compliance of the extracellular matrix. We hypothesized that in response...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774215/ https://ncbi.nlm.nih.gov/pubmed/22223454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01166.2011 |
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