Engineering a Replication-Competent, Propagation-Defective Middle East Respiratory Syndrome Coronavirus as a Vaccine Candidate

Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging coronavirus infecting humans that is associated with acute pneumonia, occasional renal failure, and a high mortality rate and is considered a threat to public health. The construction of a full-length infectious cDNA clone of the...

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Detalhes bibliográficos
Main Authors: Almazán, Fernando, DeDiego, Marta L., Sola, Isabel, Zuñiga, Sonia, Nieto-Torres, Jose L., Marquez-Jurado, Silvia, Andrés, German, Enjuanes, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774192/
https://ncbi.nlm.nih.gov/pubmed/24023385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00650-13
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