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Heavy metals zinc, cadmium, and copper stimulate pulmonary sensory neurons via direct activation of TRPA1

Airway exposure to zinc dust and zinc-containing ambient particulates can cause symptoms of airway irritation and inflammation, but the underlying molecular and cellular mechanisms are largely unknown. Transient receptor potential A1 (TRPA1) is selectively expressed in a subpopulation of pulmonary C...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gu, Qihai, Lin, Ruei-Lung
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774170/
https://ncbi.nlm.nih.gov/pubmed/20133428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01371.2009
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