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Raloxifene attenuates Gas6 and apoptosis in experimental aortic valve disease in renal failure

Renal failure is associated with aortic valve calcification. Using our rat model of uremia-induced reversible aortic valve calcification, we assessed the role of apoptosis and survival pathways in that disease. We also explored the effects of raloxifene, an estrogen receptor modulator, on valvular c...

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Detalhes bibliográficos
Main Authors: Shuvy, Mony, Abedat, Suzan, Beeri, Ronen, Valitsky, Michael, Daher, Sameh, Kott-Gutkowski, Miriam, Gal-Moscovici, Anca, Sosna, Jacob, Rajamannan, Nalini M., Lotan, Chaim
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774090/
https://ncbi.nlm.nih.gov/pubmed/21335463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00240.2010
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