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Raloxifene attenuates Gas6 and apoptosis in experimental aortic valve disease in renal failure

Renal failure is associated with aortic valve calcification. Using our rat model of uremia-induced reversible aortic valve calcification, we assessed the role of apoptosis and survival pathways in that disease. We also explored the effects of raloxifene, an estrogen receptor modulator, on valvular c...

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Autors principals: Shuvy, Mony, Abedat, Suzan, Beeri, Ronen, Valitsky, Michael, Daher, Sameh, Kott-Gutkowski, Miriam, Gal-Moscovici, Anca, Sosna, Jacob, Rajamannan, Nalini M., Lotan, Chaim
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774090/
https://ncbi.nlm.nih.gov/pubmed/21335463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00240.2010
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