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A spectrally constrained dual-band normalization technique for protoporphyrin IX quantification in fluorescence-guided surgery

We report a dual-band normalization technique for in vivo quantification of the metabolic biomarker, protoporphyrin IX (PpIX), during brain tumor resection procedures. The accuracy of the approach was optimized in tissue simulating phantoms with varying absorption and scattering properties, validate...

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Detalhes bibliográficos
Main Authors: Valdés, P. A., Leblond, F., Kim, A., Wilson, B. C., Paulsen, K. D., Roberts, D. W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774026/
https://ncbi.nlm.nih.gov/pubmed/22660039
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