Genome-wide association study in people of South Asian ancestry identifies six novel susceptibility loci for type 2 diabetes

We carried out a genome wide association study of type-2 diabetes (T2D) amongst 20,119 people of South Asian ancestry (5,561 with T2D); we identified 20 independent SNPs associated with T2D at P<10(−4) for testing amongst a further 38,568 South Asians (13,170 with T2D). In combined analysis, comm...

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Huvudupphovsmän: Kooner, Jaspal S, Saleheen, Danish, Sim, Xueling, Sehmi, Joban, Zhang, Weihua, Frossard, Philippe, Been, Latonya F, Chia, Kee-Seng, Dimas, Antigone S, Hassanali, Neelam, Jafar, Tazeen, Jowett, Jeremy BM, Li, Xinzhing, Radha, Venkatesan, Rees, Simon D, Takeuchi, Fumihiko, Young, Robin, Aung, Tin, Basit, Abdul, Chidambaram, Manickam, Das, Debashish, Grunberg, Elin, Hedman, Åsa K, Hydrie, Zafar I, Islam, Muhammed, Khor, Chiea-Chuen, Kowlessur, Sudhir, Kristensen, Malene M, Liju, Samuel, Lim, Wei-Yen, Matthews, David R, Liu, Jianjun, Morris, Andrew P, Nica, Alexandra C, Pinidiyapathirage, Janani M, Prokopenko, Inga, Rasheed, Asif, Samuel, Maria, Shah, Nabi, Shera, A Samad, Small, Kerrin S, Suo, Chen, Wickremasinghe, Ananda R, Wong, Tien Yin, Yang, Mingyu, Zhang, Fan, Abecasis, Goncalo R, Barnett, Anthony H, Caulfield, Mark, Deloukas, Panos, Frayling, Tim, Froguel, Philippe, Kato, Norihiro, Katulanda, Prasad, Kelly, M Ann, Liang, Junbin, Mohan, Viswanathan, Sanghera, Dharambir K, Scott, James, Seielstad, Mark, Zimmet, Paul Z, Elliott, Paul, Teo, Yik Ying, McCarthy, Mark I, Danesh, John, Tai, E Shyong, Chambers, John C
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773920/
https://ncbi.nlm.nih.gov/pubmed/21874001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.921
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