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STAT1, NF-κB and ERKs play a role in the induction of lipocalin-2 expression in adipocytes()
Lipocalin-2 (LCN2) is induced in conditions of obesity and Type 2 diabetes (T2DM). IFNγ and TNFα induce LCN2 expression in adipocytes in a manner that is dependent on transcription. The effects of these cytokines are additive. IFNγ induced STAT1 and TNFα induced NF-κB play a role in the induction of...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3773839/ https://ncbi.nlm.nih.gov/pubmed/24049731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.04.003 |
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