Targeting oxidized LDL improves insulin sensitivity and immune cell function in obese Rhesus macaques()

Oxidation of LDL (oxLDL) is a crucial step in the development of cardiovascular disease. Treatment with antibodies directed against oxLDL can reduce atherosclerosis in rodent models through unknown mechanisms. We demonstrate that through a novel mechanism of immune complex formation and Fc-γ recepto...

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Hlavní autoři: Li, Shijie, Kievit, Paul, Robertson, Anna-Karin, Kolumam, Ganesh, Li, Xiumin, von Wachenfeldt, Karin, Valfridsson, Christine, Bullens, Sherry, Messaoudi, Ilhem, Bader, Lindsay, Cowan, Kyra J., Kamath, Amrita, van Bruggen, Nicholas, Bunting, Stuart, Frendéus, Björn, Grove, Kevin L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773831/
https://ncbi.nlm.nih.gov/pubmed/24049738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.06.001
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