PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner

Peroxisome proliferator-activated receptorγ coactivators (PGC-1α and PGC-1β) play important roles in the transcriptional regulation of intermediary metabolism. To evaluate the effects of overexpressing PGC-1α or PGC-1β at physiologic levels in liver, we generated transgenic mice with inducible overe...

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Autori principali: Chambers, Kari T., Chen, Zhouji, Lai, Ling, Leone, Teresa C., Towle, Howard C., Kralli, Anastasia, Crawford, Peter A., Finck, Brian N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773825/
https://ncbi.nlm.nih.gov/pubmed/24049734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.05.001
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