Effect of an immune enhancer, GPI-0100, on vaccination with live attenuated herpes simplex virus (HSV) type 2 or glycoprotein D on genital HSV-2 infections of guinea pigs

These studies were performed to determine the effect of AD-472, an attenuated human herpes simplex virus (HSV) type 2 or HSV-2 glycoprotein D (gD) when combined with an adjuvant, GPI-0100, a semi-synthetic Quillaja Saponin analog in a genital HSV-2 infection in guinea pigs. While animals immunized w...

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Detalhes bibliográficos
Main Authors: Quenelle, Debra C., Collins, Deborah J., Rice, Terri L., Prichard, Mark N., Marciani, Dante J., Kern, Earl R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773812/
https://ncbi.nlm.nih.gov/pubmed/18573279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2008.05.011
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