Large-scale mutagenesis of the mouse to understand the genetic bases of nervous system structure and function

N-ethyl-N-nitrosourea (ENU) mutagenesis is presented as a powerful approach to developing models for human disease. The efforts of three NIH Mutagenesis Centers established for the detection of neuroscience-related phenotypes are described. Each center has developed an extensive panel of phenotype s...

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Bibliografiske detaljer
Main Authors: Goldowitz, Dan, Frankel, Wayne N., Takahashi, Joseph S., Holtz-Vitaterna, Martha, Bult, Carol, Kibbe, Warren A., Snoddy, Jay, Li, Yanxia, Pretel, Stephanie, Yates, Jeana, Swanson, Douglas J.
Format: Artigo
Sprog:Inglês
Udgivet: 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773686/
https://ncbi.nlm.nih.gov/pubmed/15582151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbrainres.2004.09.016
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